What Medications are used to treat depression?

11/01/2023

There are several types of medications that are commonly used to treat depression. The most common classes of medications include:

  1. Selective serotonin reuptake inhibitors (SSRIs): These medications are the most commonly prescribed type of antidepressants. They work by increasing the levels of serotonin, a neurotransmitter that helps regulate mood, in the brain. Examples of SSRIs include fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil).

  2. Serotonin and norepinephrine reuptake inhibitors (SNRIs): These medications also work by increasing the levels of neurotransmitters in the brain, but they target both serotonin and norepinephrine. Examples of SNRIs include venlafaxine (Effexor) and duloxetine (Cymbalta).

  3. Norepinephrine and dopamine reuptake inhibitors (NDRIs): This class of medication also increase the levels of norepinephrine and dopamine, two other neurotransmitters that play a role in mood regulation. Bupropion (Wellbutrin) is an example of a NDRI

  4. Tricyclic antidepressants (TCAs): These are an older class of antidepressants that work by inhibiting the reuptake of both norepinephrine and serotonin in the brain. Examples of TCAs include amitriptyline and imipramine.

  5. Monoamine oxidase inhibitors (MAOIs): This class of antidepressant medications works by inhibiting the activity of an enzyme called monoamine oxidase, which breaks down neurotransmitters in the brain. Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate).

It's important to note that the choice of medication, the dosage, the duration and schedule will depend on the specific case, the symptoms and the preferences of the patient. Additionally, therapy such as cognitive behavioral therapy (CBT) or talk therapy can be combined with medication for better results. It's also important to work closely with a healthcare professional to monitor the progress and adjust the treatment as needed.

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